Non-steroidal anti-inflammatory drug

Aceclofenac (أسيكلوفيناك)

Aceclofenac is a painkiller and anti-inflammatory used for painful inflammatory joint and muscle conditions. Tablets can cause stomach bleeding and kidney or cardiovascular problems; absorption from cream is lower but it is not risk-free.

What it is used for

  • Relieving pain and inflammation in osteoarthritis
  • Treating symptoms of rheumatoid arthritis and ankylosing spondylitis
  • Cream for local relief of muscle and joint pain and inflammation in authorised products

How it is used

  • Swallow the tablet with water, with or after food, as prescribed
  • Use the minimum treatment your clinician decides and do not combine it with a similar painkiller
  • Apply a thin layer of cream to intact skin and rub in gently as directed by the leaflet
  • Wash your hands after cream and avoid the eyes, wounds and airtight dressings

Possible side effects

  • Indigestion, stomach pain, nausea or diarrhoea
  • Dizziness or headache
  • Rash, itching or local irritation with cream
  • An ulcer or bleeding in the stomach or bowel
  • Fluid retention, raised blood pressure or a change in kidney function

Who should not use it

  • Allergy to aceclofenac or asthma or rash triggered by aspirin or a similar painkiller
  • Current or recurrent stomach or bowel ulceration or bleeding
  • Severe heart, kidney or liver failure
  • The final trimester of pregnancy

Before and while using it

  • Get urgent help for black stools, vomiting blood, chest pain or sudden weakness
  • Extra care is needed in older people and those with asthma, high blood pressure, or heart, kidney or liver disease
  • It may increase heart attack or stroke risk, particularly with higher or prolonged exposure
  • Stop and seek medical advice for a severe rash, blistering, swelling or breathing difficulty
  • Cream may make the skin more sensitive to sunlight in some people

Medicine interactions

  • Anticoagulants and antiplatelet medicines can increase bleeding
  • Other NSAIDs, aspirin, corticosteroids and some antidepressants increase ulcer and bleeding risk
  • Diuretics and blood-pressure medicines may work less well and kidney injury risk can rise
  • Lithium, methotrexate and some immunosuppressants can have increased levels or toxicity

Pregnancy and breastfeeding

  • Avoid it during pregnancy unless a clinician considers it necessary, and do not use it in the final trimester
  • Ask your doctor for an alternative while breastfeeding or when trying to conceive

How to store it

  • Store as directed by the leaflet, away from heat, moisture and children's reach

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.