Herbal medicine for premenstrual symptoms

Agnus castus fruit dry extract (خلاصة ثمار كف مريم)

Agnus castus fruit is a standardised herbal extract that may relieve premenstrual-syndrome symptoms in adult women. Extracts differ in composition and strength of evidence and may affect prolactin, dopamine and hormone pathways.

What it is used for

  • Relieving premenstrual-syndrome symptoms such as mood irritability, headache and breast fullness
  • Relieving recurring minor symptoms before a period when a suitable herbal preparation is used

How it is used

  • Swallow the tablet or capsule with water and follow the leaflet for the specific preparation
  • Use it consistently as the leaflet directs and do not take extra after a missed amount
  • Record symptom and period timing so response can be reviewed with a doctor or pharmacist
  • See a doctor if symptoms worsen, persist or the period pattern becomes unusual
  • Do not combine it with another agnus castus extract because preparations are not equivalent

Possible side effects

  • Nausea or abdominal pain
  • Headache or dizziness
  • Rash, itching or acne
  • Menstrual disturbance
  • Rarely, severe allergy with facial swelling or difficulty breathing or swallowing

Who should not use it

  • Allergy to agnus castus fruit or any product ingredient

Before and while using it

  • A breast lump, unusual bleeding, severe pain or new symptoms need examination and should not automatically be attributed to premenstrual syndrome
  • Ask a doctor before use if you have a hormone-sensitive tumour or a pituitary disorder
  • The extract could mask symptoms of a prolactin-secreting tumour or affect its treatment
  • Suitability in children or adolescents is not established; herbal monographs cover adult women
  • Different herbal preparations are not interchangeable because extraction and concentration affect evidence and safety

Medicine interactions

  • Dopamine agonists and antagonists may interact and need medical review
  • Oestrogens, antioestrogens and other hormone treatments may be affected or alter its effect
  • Tell the doctor about all herbs and supplements because interaction data are limited

Pregnancy and breastfeeding

  • Do not use it during pregnancy; stop and contact a doctor if pregnancy occurs
  • It is not recommended during breastfeeding because it may affect prolactin and milk production and infant information is limited

How to store it

  • Keep the product dry in its original pack at the temperature stated in the leaflet, out of children's reach

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.