What it is used for
- Routine prevention of bleeding in people with haemophilia B
- Treatment of bleeding episodes when they occur
- Prevention and control of bleeding before, during and after surgery
How it is used
- The haemophilia centre sets the plan and dose from the clinical situation and test results
- The powder is mixed with its supplied solvent and injected into a vein after training; a patient or caregiver may give it if the team approves
- Use only the pack equipment, inspect the solution and do not use it if cloudy or particulate
- Record the product name and batch number with every injection and report every bleed to the centre
- Do not mix it with other medicines in the syringe or intravenous line
Possible side effects
- Headache or dizziness
- Injection-site reaction
- Rash or itching
- Development of antibodies that reduce factor IX effectiveness
- Rare severe hypersensitivity or thrombosis
Who should not use it
- Allergy to albutrepenonacog alfa or any product ingredient
- Known allergy to hamster proteins
Before and while using it
- Stop the injection and seek urgent help for breathing difficulty, facial swelling, hives or severe dizziness
- If bleeding does not respond as usual, factor IX antibodies may have developed; contact the centre immediately
- Thrombosis risk can rise in selected patients, especially with liver disease, after surgery, in newborns or with other risk factors
- An intravenous access device requires monitoring for infection and clots
- Do not change factor IX product or the prevention plan without the haemophilia team
- Keep a record of the product name and batch number for traceability
Medicine interactions
- No important medicine interactions are known, but tell the haemophilia centre about all medicines and supplements
- Anticoagulants and antiplatelet medicines can increase bleeding and require specialist supervision
- Do not mix it with another product in the same syringe or infusion line
Pregnancy and breastfeeding
- Haemophilia B is rare in women and pregnancy data are limited; use only when a specialist identifies a clear need
- Tell the team if you are breastfeeding so treatment benefit can be weighed against limited information on transfer into milk
How to store it
- Keep in the original pack protected from light under the labelled refrigeration or temperature conditions; do not freeze, and use the prepared solution as the leaflet directs
Get medical help straight away if
- Your face, lips or tongue swell, or you find it hard to breathe.
- You get a severe rash, blistering or peeling skin.
- A side effect worries you or doesn’t go away: contact your doctor or pharmacist.
Questions about this medicine?
Talk to a doctor by video, or send your question by text.
Source: Standard international medicine references
This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.