Bone-strengthening medicine (bisphosphonate)

Alendronic acid (alendronate) (ألندرونات)

Alendronate slows the breakdown of bone, which makes bones denser and lowers the risk of fractures. It is mainly used to treat and prevent osteoporosis and needs to be taken in a special way.

What it is used for

  • Treating osteoporosis in women after the menopause
  • Treating osteoporosis in men
  • Treating or preventing osteoporosis caused by corticosteroid medicines
  • Treating Paget's disease of bone

How it is used

  • Use it only as prescribed by your doctor; your doctor decides the dose and schedule
  • Take the tablet as soon as you get up, on an empty stomach, with a full glass of plain water only, not tea, coffee, juice, milk or mineral water
  • Swallow the tablet whole without chewing or sucking it; effervescent tablets are dissolved in plain water as the leaflet says
  • Stay sitting or standing and do not lie down, eat, drink or take other medicines until the time stated in the leaflet has passed
  • Do not take it at bedtime or before you get up for the day

Possible side effects

  • Stomach pain, heartburn, indigestion or bloating
  • Bone, muscle or joint pain
  • Difficulty or pain when swallowing, or pain behind the breastbone, which can mean irritation of the gullet
  • Headache

Who should not use it

  • Do not use it if you are allergic to the active ingredient or any other ingredient in the product
  • Problems of the gullet that slow the passage of food, such as narrowing
  • Being unable to sit or stand upright for a while after taking it
  • Low blood calcium

Before and while using it

  • Stop it and contact your doctor if you get pain on swallowing, new or worse heartburn, or chest pain
  • Rarely, it can damage the jawbone; have a dental check before treatment, keep your mouth clean and tell your dentist you take it
  • Tell your doctor about any new thigh, hip or groin pain, which can rarely be a sign of an unusual thigh-bone fracture
  • Tell your doctor about ear pain or discharge
  • You usually need enough calcium and vitamin D; ask your doctor
  • Tell your doctor if you have kidney disease

Medicine interactions

  • Calcium, antacids, iron and other supplements reduce its absorption; take them later in the day
  • Anti-inflammatory painkillers such as ibuprofen can add to stomach irritation
  • Tell your doctor or pharmacist about all the medicines, supplements and herbal products you take

Pregnancy and breastfeeding

  • It is not used during pregnancy or breastfeeding

How to store it

  • Store at room temperature away from heat and moisture, out of the sight and reach of children.

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.