Allergen immunotherapy (desensitisation)

Allergen extracts (sublingual drops) (مستخلصات مسببات الحساسية تحت اللسان)

These drops contain small, measured amounts of the substances you are allergic to, such as pollens, moulds or animal dander. They are held under the tongue regularly over a long period to get the immune system used to them and reduce allergy symptoms. An allergy specialist starts and supervises them after tests confirm the allergy; treatment begins with the starting bottle and continues with the maintenance bottle.

This medicine is used under close medical supervision, usually by a specialist. Never start, stop or change it without your doctor.

What it is used for

  • Allergic rhinitis and conjunctivitis caused by a confirmed allergen when usual medicines are not enough
  • Add-on treatment for mild, controlled allergic asthma, as the allergy specialist decides
  • Reducing the need for allergy medicines in the long term

How it is used

  • Start it only under an allergy specialist; the first dose is often given in the clinic
  • Put the drops under the tongue with the pump, hold them there for the time in the leaflet, then swallow
  • Follow the build-up schedule with the starting bottle and then the maintenance bottle exactly, without skipping steps
  • If you miss several doses, ask your specialist before restarting

Possible side effects

  • Itching or swelling in the mouth or under the tongue
  • Throat irritation
  • Stomach ache or nausea
  • A temporary increase in allergy symptoms such as sneezing
  • Rarely, a severe allergic reaction

Who should not use it

  • Severe or uncontrolled asthma
  • Active cancer or severe immune system diseases
  • Severe mouth inflammation or ulcers (treatment is paused)
  • Allergy to any ingredient other than the intended allergen

Before and while using it

  • Breathlessness, difficulty swallowing, throat swelling or a widespread rash need emergency help at once
  • Pause it and ask your specialist if you have mouth wounds, a tooth extraction, an acute infection or an asthma attack
  • Tell your specialist if your asthma gets worse during treatment
  • Benefit builds up gradually and needs long-term use as your specialist decides

Medicine interactions

  • Beta-blockers can make a severe allergic reaction harder to treat; tell the allergy specialist about all your medicines
  • Tell your specialist if you are having any other allergy immunotherapy

Pregnancy and breastfeeding

  • Treatment is not started in pregnancy; if you become pregnant during treatment your specialist decides whether to continue
  • Ask your doctor if you are breastfeeding

How to store it

  • Keep the bottles in the fridge, do not freeze them, and keep them out of the reach of children

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.