Stimulant laxative (anthraquinone)

Aloin (aloe laxative) (ألوين)

Aloin is the bitter laxative substance in the sap of aloe leaves. It stimulates the bowel and usually works within hours. It is combined with belladonna, which reduces cramping. It is only for short-term relief of occasional constipation; modern laxatives such as senna or bisacodyl are preferred because there are safety concerns about long-term use of aloe substances.

What it is used for

  • Short-term relief of occasional constipation
  • Constipation that has not improved with more fibre, fluids and activity, for a short time only

How it is used

  • Swallow the tablets whole with water, usually at bedtime; follow the leaflet and ask your pharmacist
  • Use it for a short time only, and see your doctor if you keep needing it
  • Drink enough fluids and eat a diet rich in fibre

Possible side effects

  • Abdominal cramps
  • Diarrhoea and loss of fluid and potassium
  • From belladonna: dry mouth, blurred vision, difficulty passing urine and a fast heartbeat
  • Red-brown urine, which is harmless

Who should not use it

  • Blocked bowel, appendicitis or unexplained abdominal pain
  • Inflammatory bowel disease such as Crohn's disease and ulcerative colitis
  • Children
  • Angle-closure glaucoma, an enlarged prostate or urinary retention, because of the belladonna

Before and while using it

  • Long-term use can make the bowel sluggish and lower potassium
  • See your doctor if constipation continues, your bowel habit changes or there is blood in the stool
  • European authorities have restricted aloe laxative substances in food supplements because of safety concerns
  • Ask your doctor first if you have heart disease, because of the belladonna

Medicine interactions

  • Water tablets and steroids can increase potassium loss
  • Low potassium increases the risk of side effects from digoxin and heart rhythm medicines
  • Other anticholinergic medicines add to the effects of belladonna

Pregnancy and breastfeeding

  • It is not used in pregnancy or breastfeeding; ask your doctor about a suitable laxative

How to store it

  • Keep the tablets in a dry place out of the reach of children

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.