What it is used for
- Add-on treatment for active systemic lupus erythematosus despite usual treatment
- Reducing flares and the need for steroids
How it is used
- It is given as a drip into a vein by a nurse or doctor at regular intervals set by your doctor
- Continue your other lupus medicines as prescribed
- Attend regular check-ups and tests
Possible side effects
- Nose and throat infections and bronchitis
- Shingles
- Infusion reactions such as headache and nausea
- Cough
- Allergic reactions
Who should not use it
- Allergy to anifrolumab or any of its ingredients
Before and while using it
- Tell your doctor about fever or any signs of infection; treatment is not started during a serious active infection
- Report a painful blistering rash on one side of the body, which may be shingles
- You are checked for tuberculosis before treatment, and live vaccines are avoided
- It has not been studied in severe active lupus nephritis or severe lupus of the nervous system
Medicine interactions
- Do not combine it with other biologic lupus medicines such as belimumab
- Live vaccines
Pregnancy and breastfeeding
- Information is limited; it is avoided in pregnancy unless your doctor decides the benefit is greater, so tell them if you plan a pregnancy
- Ask your doctor if you are breastfeeding
How to store it
- It is kept in the fridge and prepared in hospital
Get medical help straight away if
- Your face, lips or tongue swell, or you find it hard to breathe.
- You get a severe rash, blistering or peeling skin.
- A side effect worries you or doesn’t go away: contact your doctor or pharmacist.
Questions about this medicine?
Talk to a doctor by video, or send your question by text.
Source: Standard international medicine references
This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.