Ocular antihistamine

Antazoline (أنتازولين)

Antazoline is an antihistamine that relieves itching and redness caused by eye allergy. It is usually supplied in combination with an ocular decongestant, so warnings also depend on the other ingredient.

What it is used for

  • Temporary relief of itchy, red eyes from seasonal or persistent allergy
  • Relief of congestion and inflammation in allergic conjunctivitis as part of a combination eye drop

How it is used

  • Use the drops as the leaflet or clinician advises and only for short-term relief
  • Wash your hands, remove contact lenses and do not touch the bottle tip to the eye or fingers
  • Place the drop in the lower-eyelid pocket, close the eye and press gently at the inner corner to reduce absorption
  • Leave the interval advised by the pharmacist between this and another eye drop
  • Do not share the bottle and discard it after the post-opening period stated in the leaflet

Possible side effects

  • Stinging, burning or temporary blurred vision
  • Slight pupil enlargement or dry eye
  • Headache or sleepiness
  • Palpitations, raised blood pressure or dizziness if the decongestant ingredient is absorbed
  • Rarely, severe allergy or increased eye redness

Who should not use it

  • Allergy to antazoline, its companion active ingredient or any component
  • Narrow-angle glaucoma
  • Wearing contact lenses during use
  • Use of monoamine-oxidase inhibitors or the recent period after stopping them when the drops contain a decongestant

Before and while using it

  • Eye pain, light sensitivity, discharge, injury or a change in sight needs examination rather than self-treatment
  • Do not use for a prolonged period because a decongestant can cause rebound or worsening redness
  • Ask a clinician first if you have heart disease, high blood pressure, diabetes, an overactive thyroid or difficulty urinating
  • Stop and seek advice if redness worsens or symptoms do not improve within the leaflet's short treatment period
  • Do not drive until any blurred vision has cleared

Medicine interactions

  • Monoamine-oxidase inhibitors and some antidepressants can increase the decongestant's heart and blood-pressure effects
  • Blood-pressure medicines, stimulants and other decongestants need pharmacist review
  • Separate it from other eye drops as directed by a clinician or pharmacist

Pregnancy and breastfeeding

  • Information is limited; ask a clinician or pharmacist before use in pregnancy or breastfeeding and avoid prolonged use

How to store it

  • Keep the bottle closed as the leaflet directs, away from light and children's reach; do not use if the solution changes appearance

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.