Erectile dysfunction medicine (PDE5 inhibitor)

Avanafil (أفانافيل)

Avanafil helps men with erectile dysfunction get an erection when they are sexually aroused, by increasing blood flow to the penis. It does not work without sexual arousal and does not protect against sexually transmitted infections.

What it is used for

  • Treating erectile dysfunction in adult men
  • Helping achieve an erection firm enough for sex when sexually aroused

How it is used

  • Use it only as prescribed by your doctor; your doctor decides the dose.
  • Swallow the tablet whole with water a short time before sexual activity, as the leaflet explains, with or without food.
  • Do not take more than the prescribed dose in one day.

Possible side effects

  • Headache and flushing
  • Stuffy nose
  • Back pain or dizziness

Who should not use it

  • Do not use it if you take nitrate medicines for angina (such as nitroglycerin) or riociguat
  • Do not use it if your doctor has advised you to avoid sexual activity because of heart disease, or after a recent heart attack or stroke
  • Do not use it if you have lost sight in an eye because of a blood-flow problem in the optic nerve
  • Do not use it if you are allergic to the active ingredient or any other ingredient in the product

Before and while using it

  • Get medical help immediately if an erection lasts a long time or is painful.
  • Stop it and get help immediately if you suddenly lose vision or hearing.
  • Tell your doctor if you have heart disease, low blood pressure, uncontrolled high blood pressure, or liver or kidney disease.
  • If you get chest pain during sexual activity, stop and get medical help, and do not take nitrates.

Medicine interactions

  • Nitrates and riociguat can cause a dangerous drop in blood pressure and must not be used with it.
  • Alpha-blockers for the prostate or blood pressure (such as doxazosin and tamsulosin) can lower blood pressure further.
  • Some antifungals, antibiotics and HIV medicines (such as ketoconazole, clarithromycin and ritonavir) raise its level in the blood.
  • Heavy drinking or grapefruit juice can increase side effects.

Pregnancy and breastfeeding

  • This medicine is for men and is not used by women.

How to store it

  • Store at room temperature away from heat and moisture, out of the sight and reach of children.

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.