Short-acting topical ocular anaesthetic

Benoxinate (oxybuprocaine) (بينوكسينات)

Benoxinate, also called oxybuprocaine, is a short-acting local anaesthetic for the eye surface used by a professional during examination or a minor procedure. It is not supplied for repeated home use because misuse can damage the cornea and hide injury.

This medicine is used under close medical supervision, usually by a specialist. Never start, stop or change it without your doctor.

What it is used for

  • Anaesthesia of the eye surface for pressure measurement or other diagnostic examinations
  • Anaesthesia for superficial foreign-body removal or a minor procedure selected by an eye professional
  • Ocular anaesthesia with fluorescein dye for corneal examination in combination products

How it is used

  • A doctor or trained nurse places it in the eye only when needed for the procedure
  • Remove contact lenses and do not replace them until anaesthesia has worn off and the professional permits it
  • Do not touch or rub the numb eye; protect it from dust and injury until sensation and normal vision return
  • A single-dose container is used immediately after opening and the professional discards any remainder
  • Do not take the bottle home or repeat the drop to relieve eye pain

Possible side effects

  • Temporary stinging or burning on instillation
  • Temporary blurred vision or eye redness
  • Eye pain, irritation or allergic inflammation
  • Corneal erosion, inflammation or clouding with misuse
  • Rare severe allergy

Who should not use it

  • Allergy to benoxinate, a related local anaesthetic or any drop ingredient
  • Self-treatment or repeated use for eye pain outside a professionally supervised procedure

Before and while using it

  • Prolonged or repeated use can cause corneal ulceration, scarring, perforation and loss of vision
  • A numb eye can be scratched, contaminated or burned without warning; do not rub or touch it
  • Do not drive or use machinery until normal vision has fully returned
  • Tell the professional about eye infection, injury or recent surgery and any allergy to local anaesthetics
  • Swallowing the drops or excessive use can cause systemic toxicity and needs urgent help
  • Seek urgent assessment if pain, redness or blurred vision persists after anaesthesia wears off

Medicine interactions

  • It is incompatible with silver nitrate, mercury salts and alkaline substances
  • Avoid ophthalmic products containing chlorhexidine acetate with it
  • Tell the eye professional about every other eye drop; the professional arranges their use during the procedure

Pregnancy and breastfeeding

  • Use during pregnancy only if the doctor considers the procedure essential and benefit outweighs risk
  • Use while breastfeeding only when necessary and directed by the doctor

How to store it

  • Clinical staff store the product as the leaflet directs and do not freeze it; a single-dose container is used immediately after opening

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.