Plant sterol used in prostate supplements and skin products

Beta-sitosterol (بيتا سيتوستيرول)

Beta-sitosterol is a cholesterol-like plant substance included in some supplements for benign prostate symptoms and in some skin products. It may modestly improve urinary symptoms in some men, but it does not shrink the prostate or replace medical assessment. Evidence for topical uses varies by product.

What it is used for

  • A supplement that may help some urinary symptoms of benign prostate enlargement, with limited evidence
  • An ingredient in certain creams and gels intended to protect skin or care for minor wounds, according to the licensed product

How it is used

  • For oral supplements, follow the leaflet, ask a pharmacist and tell your doctor if you use it for urinary symptoms
  • Do not use it instead of a prostate assessment or prescribed medicine, and do not delay assessment of difficulty urinating
  • Apply cream or gel as the leaflet directs, avoiding the eyes and deep or infected wounds unless medically advised

Possible side effects

  • Nausea, indigestion, diarrhoea or constipation with supplements
  • Reduced sexual desire or performance in some people
  • Skin irritation or redness with topical products
  • Rarely, an allergic reaction

Who should not use it

  • Sitosterolaemia, a rare inherited condition in which plant sterols accumulate
  • Allergy to the substance or any product ingredient

Before and while using it

  • See a doctor promptly if you cannot pass urine or develop blood in the urine, pain or fever; these are not symptoms for self-treatment
  • Urinary symptoms can have other causes and need assessment before relying on a supplement
  • Supplement quality and composition vary, and natural does not mean safe for everyone
  • Do not put a topical product on a severe burn or deep wound instead of obtaining medical care

Medicine interactions

  • Medicines that block cholesterol absorption may reduce plant-sterol absorption or alter its effect
  • Tell your doctor or pharmacist about all prostate supplements to avoid duplicated ingredients

Pregnancy and breastfeeding

  • There is not enough information about the supplement in pregnancy or breastfeeding; avoid it unless advised by a professional, and ask before using a topical product

How to store it

  • Store as the pack directs, away from heat and moisture and out of children's reach

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.