Enzyme from pineapple used to reduce swelling

Bromelain (بروميلين)

Bromelain is an enzyme taken from the pineapple plant. It is often combined with other enzymes such as trypsin to help reduce swelling and bruising after injuries or operations. The evidence that it helps is limited.

What it is used for

  • Helping reduce swelling and bruising after injuries, operations or dental treatment, as an add-on treatment
  • In some digestive-enzyme products to help digestion; the evidence is limited

How it is used

  • Take it as your doctor prescribed or as the leaflet says; ask your pharmacist
  • Coated tablets are swallowed whole with water, not broken or chewed
  • Sachets are dissolved in water before drinking, as the leaflet says

Possible side effects

  • Stomach upset, nausea or diarrhoea
  • Allergic reactions such as rash or itching, especially in people allergic to pineapple

Who should not use it

  • Do not use it if you are allergic to pineapple or any ingredient in the product
  • Do not use it if you have a bleeding or clotting disorder, unless your doctor advises it

Before and while using it

  • It may raise the risk of bleeding; tell your doctor or dentist you take it before any operation
  • The evidence that it helps is limited, and it does not replace treating the cause of the swelling
  • See a doctor if the swelling or pain gets worse or you get a fever or redness
  • It may cause allergy in people allergic to latex, pollen or wheat

Medicine interactions

  • It may increase bleeding with blood thinners such as warfarin, aspirin and clopidogrel
  • It may increase the absorption of some antibiotics such as amoxicillin and tetracyclines; tell your doctor

Pregnancy and breastfeeding

  • There is not enough information on its safety in pregnancy and breastfeeding; use it only if your doctor advises it

How to store it

  • Store at room temperature away from heat and moisture, out of the sight and reach of children.

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.