Prostaglandin that makes the womb contract

Carboprost (كاربوبروست)

Carboprost is a prostaglandin medicine that makes the muscle of the womb contract strongly. It is used in hospital to stop heavy bleeding after childbirth when other medicines have not worked.

This medicine is used under close medical supervision, usually by a specialist. Never start, stop or change it without your doctor.

What it is used for

  • Treating heavy bleeding after childbirth caused by a slack womb when first-line medicines have not worked
  • In some countries, ending a pregnancy in hospital in specific situations

How it is used

  • It is injected into a muscle, or sometimes into the womb muscle, by a doctor in hospital, and the dose may be repeated as needed
  • The medical team watches bleeding, blood pressure and breathing after the injection

Possible side effects

  • Nausea, vomiting and diarrhoea
  • Fever, chills or flushing
  • Narrowing of the airways and wheezing
  • Raised blood pressure

Who should not use it

  • It is not given to people with asthma or active lung disease
  • It is not given with active severe heart, liver or kidney disease
  • Do not use it if you are allergic to this medicine or any ingredient in the product

Before and while using it

  • Tell the medical team if you have asthma, high blood pressure, epilepsy or diabetes
  • Tell the medical team straight away if you feel short of breath or have chest pain

Medicine interactions

  • It can add to the effect of other medicines that make the womb contract, such as oxytocin
  • Tell your doctor or pharmacist about all your medicines, including herbal products and supplements

Pregnancy and breastfeeding

  • It is used after childbirth to stop bleeding; it is not used during a wanted pregnancy because it makes the womb contract, and breastfeeding can usually continue

How to store it

  • The hospital or pharmacy stores it in the fridge as the maker directs; it must not be frozen.

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.