Recombinant human chorionic gonadotropin (fertility hormone)

Choriogonadotropin alfa (recombinant hCG) (كوريوجونادوتروبين ألفا)

Choriogonadotropin alfa is a man-made form of the pregnancy hormone hCG. It is given as a single injection under the skin, at a time set by the fertility clinic, to complete egg maturation and trigger ovulation.

This medicine is used under close medical supervision, usually by a specialist. Never start, stop or change it without your doctor.

What it is used for

  • Completing egg maturation before egg collection in IVF or ICSI
  • Triggering ovulation in women having treatment to stimulate ovulation

How it is used

  • Use it only as prescribed by your fertility doctor
  • It is injected under the skin at the exact time the clinic gives you; timing is very important for the treatment to work
  • A nurse will show you how to inject it; follow the leaflet

Possible side effects

  • Pain or redness where it is injected
  • Headache or tiredness
  • Nausea or stomach pain
  • Ovarian hyperstimulation

Who should not use it

  • Do not use it if you are allergic to the active ingredient or any other ingredient in the product
  • Tumours of the hypothalamus, pituitary gland, ovary, womb or breast
  • Ovarian enlargement or cysts not due to polycystic ovaries, or unexplained vaginal bleeding
  • Early ovarian failure

Before and while using it

  • Get help straight away for severe stomach pain or swelling, vomiting, breathlessness or rapid weight gain
  • It increases the chance of twins or more
  • A pregnancy test can be falsely positive for a while after the injection; follow the clinic's advice on when to test
  • Tell your doctor if you or your family have a history of blood clots

Medicine interactions

  • It can affect pregnancy test results
  • Tell your doctor or pharmacist about all the medicines, supplements and herbal products you take

Pregnancy and breastfeeding

  • It is not used during pregnancy or breastfeeding

How to store it

  • Keep it in a refrigerator without freezing in the original pack; the leaflet may allow a limited time at room temperature

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.