Antioxidant used for nerve symptoms

Alpha-lipoic acid (thioctic acid) (حمض ألفا ليبويك)

Alpha-lipoic acid (thioctic acid) is an antioxidant that the body makes naturally. It is widely used for tingling, burning and numbness caused by nerve damage from diabetes; studies suggest a modest benefit for symptoms in some people.

What it is used for

  • Easing tingling, burning, pain or numbness from diabetic nerve damage (peripheral neuropathy), alongside good blood sugar control
  • Sometimes used for other nerve problems, where evidence is limited

How it is used

  • Tablets and capsules are swallowed whole with water, often on an empty stomach before a meal as the leaflet says, because food can reduce absorption
  • Effervescent tablets and sachets are dissolved fully in water before drinking
  • Use it as your doctor or pharmacist advises, and keep taking your diabetes medicines

Possible side effects

  • Nausea, stomach pain or diarrhoea
  • Skin rash or itching
  • Headache
  • Low blood sugar in people with diabetes (sweating, shaking, hunger, confusion)

Who should not use it

  • Do not use it if you are allergic to alpha-lipoic acid or any ingredient in the product

Before and while using it

  • It may lower blood sugar; check your sugar more often when you start it if you take diabetes medicines or insulin
  • It does not replace good blood sugar control, which is the main way to protect the nerves
  • Avoid alcohol, which makes nerve damage worse
  • See your doctor about new numbness, weakness or wounds on the feet
  • Rarely it has been linked to repeated low blood sugar caused by insulin antibodies; get medical help for repeated unexplained low sugars

Medicine interactions

  • Diabetes medicines and insulin: risk of low blood sugar
  • It may bind iron, magnesium and calcium; take it at a different time from mineral supplements and dairy products
  • Tell your doctor or pharmacist about all your medicines and supplements

Pregnancy and breastfeeding

  • There is not enough information on its safety in pregnancy or breastfeeding; use it only if your doctor advises it

How to store it

  • Store at room temperature away from heat and moisture, out of the sight and reach of children.

Get medical help straight away if

  • Your face, lips or tongue swell, or you find it hard to breathe.
  • You get a severe rash, blistering or peeling skin.
  • A side effect worries you or doesn’t go away: contact your doctor or pharmacist.

Questions about this medicine?

Talk to a doctor by video, or send your question by text.

Source: Standard international medicine references

This guide is general information and doesn’t replace advice from your doctor or pharmacist. Don’t start, stop or change a medicine without asking them, and always read the leaflet in the pack.